Table 4.

Pathologic findings on kidney specimens in 13 adult patients with CFa

PatientLight MicroscopyImmunofluorescenceDiagnosis
Glomeruli (Sclerotic Glomeruli)Tubules/InterstitiumVessels
1Endocapillary proliferation, mesangial neutrophils infiltrationGlomerular C3 deposits, humpsPostinfectious GN
2FSGSci2/ct2 calcium oxalate crystalsah0/cv0NegativeFSGS
3KW (6/17)ci2/ct2ah2/cv1Linear IgA, IgG, and albumin depositsDiabetic glomerulopathy
4KW (1/17)ci1/ct1ah3/cv1Linear IgA, IgG, and albumin depositsDiabetic glomerulopathy
5Mesangial and subepithelial amyloid deposits (7/20)ci2/ct2 amyloid depositsah2/cv2 amyloid depositsAA amyloidosisDiffuse amyloidosis AA subtype
6Normal (1/3)ci1/ct1ah0/cv0NegativeMCD/CTIN
7Diffuse mesangial proliferation (0/18)ci1/ct0ah0/cv1Mesangial IgA depositsIgAN
8Normal (0/16)i0/t0ah0/cv1Subepithelial IgG depositsMN
9Mesangial amyloid deposits (2/14)i0/t0 intratubular vacuolesArteriolar amyloidosisAA amyloidosisDiffuse amyloidosis AA subtype
10FSGS (1/14)ci1/ct0ah1/cv0NegativeFSGS
11KW (0/10)ci1/ct1ah0/cv1Linear IgA, IgG, and albumin depositsDiabetic glomerulopathy
12Normal (2/21)ci2/ct2ah0/cv0 cellular infiltrate, intratubular pigmentsNegativeCTIN
13Mesangial and subepithelial amyloidosis (4/23)ci2/ct2 amyloidosisAmyloidosis ah2/cv1AA amyloidosisDiffuse amyloidosis AA subtype
  • a ah, arteriolar hyaline thickening; ci, interstitial fibrosis; ct, tubular atrophy; cv, vacular fibrous intimal thickening.