Table 3.

Median values of serum and urinary parametersa

ParameterADPKD + LIT (n = 35; Median [Range])ADPKD (n = 90; Median [Range])P
Serum
    creatinine (mg/dl)1.1 (0.7 to 6.6)1.1 (0.7 to 4.4)0.31
    sodium (mEq/L)140 (134 to 146)141 (135 to 148)0.19
    potassium (mEq/L)4.2 (3.3 to 5.9)4.3 (3.3 to 5.2)0.10
    calcium (mg/dl)9.1 (8.4 to 9.9)9.3 (8.1 to 10.4)0.13
    uric acid (mg/dl)5.2 (2.4 to 9.5)4.9 (1.5 to 8.6)0.37
    chloride (mmol/L)105 (102 to 113)106 (61 to 117)0.77
    HCO3, plasma (mEq/L)25 (20 to 30)26 (20 to 32)0.34
Urine
    volume (ml/d)1840 (590 to 3560)1510 (430 to 4300)0.64
    calcium (mg/d)112 (39 to 274)102 (6 to 285)0.39
    uric acid (mg/d)469 (134 to 1047)497 (171 to 1141)0.92
    citrate (mg/d)295 (89 to 922)301 (78 to 923)0.97
    oxalate (mg/d)31 (19 to 66)25 (10 to 65)0.03
    sodium (mEq/d)172 (76 to 388)202 (52 to 410)0.51
    potassium (mEq/d)52 (18 to 94)44 (13 to 130)0.28
    creatinine (mg/d)1203 (682 to 2226)1241 (525 to 2964)0.40
    urea (g/d)16.0 (1.3 to 44.0)14.0 (12.0 to 42.0)0.46
    magnesium (mg/d)79 (41 to 163)79 (18 to 149)0.29
    phosphate (mg/d)771 (368 to 1621)629 (123 to 1614)0.08
    APCaOx index0.9 (0.4 to 2.6)0.8 (0.2 to 3.7)0.22
    fasting upH5.7 (4.9 to 6.8)5.6 (4.7 to 8.0)0.63
    NH4 (μEq/min) after NH4Cl load31 (23 to 74)42 (20 to 59)0.24
  • a AP, activity product; upH, urinary pH.