Table 1.

Baseline demographic and clinical characteristicsa

CharacteristicCinacalcet(n = 507)Control(n = 383)
Gender (n [%])
    men328 (64.7)245 (64.0)
    women179 (35.3)138 (36.0)
Race (n [%])
    black263 (51.9)159 (41.5)
    other244 (48.1)224 (58.5)
Age (yr; mean [SD])52.3 (14.4)55.1 (14.5)
BMI (kg/m2; mean [SD])27.4 (6.8)27.2 (6.3)
Time on dialysis (yr; median [IQR])4.0 (1.9 to 7.6)3.8 (1.9 to 7.8)
iPTH (pg/ml; median [IQR])601 (431 to 871)548 (408 to 758)
Serum calcium (mg/dl; median [IQR])9.8 (9.3 to 10.4)9.8 (9.4 to 10.4)
Serum phosphorus (mg/dl; median [IQR])6.0 (5.1 to 7.3)6.1 (5.1 to 7.1)
Serum Ca × P (mg2/dl2; median [IQR])60.2 (48.9 to 71.7)60.3 (50.0 to 70.6)
Serum AP (U/L; median [IQR])111 (81 to 153)99 (77 to 143)
Medical history (n [%])
    diabetes157 (31.0)118 (30.8)
    cardiovascular diseaseb242 (47.7)206 (53.8)
  • a To convert serum calcium in mg/dl to mmol/L, multiply by 0.2495; serum phosphorus in mg/dl to mmol/L, multiply by 0.3229. AP, alkaline phosphatase; BMI, body mass index; Ca × P, calcium-phosphorus product; iPTH, intact parathyroid hormone; IQR, interquartile range.

  • b Includes cerebrovascular accident, peripheral vascular disease, myocardial infarction, coronary artery disease, and congestive heart failure.