Table 3.

Functional assessment by study population, adjusted resultsa

ParameterRenal FailureHeart FailureCOPDHigh CV Risk
Total disability score (PAT-D) (1 to 5)Adjusted mean (SE)1.42 (0.11)1.78 (0.10)1.87 (0.05)1.47 (0.04)
P value compared with Renal Failure0.04010.00031.0000
SPPB score (0 to 12)Adjusted mean (SE)8.42 (0.30)9.92 (0.24)10.17 (0.18)10.18 (0.11)
P value compared with Renal Failure0.0003<0.0001<0.0001
Gait speed (m/s)Adjusted mean (SE)0.80 (0.04)1.20 (0.03)0.96 (0.02)1.22 (0.02)
P value compared with Renal Failure<0.00010.0053<0.0001
Five chair-rise time (s)Adjusted mean (SE)15.92 (0.86)14.68 (0.63)14.00 (0.46)14.38 (0.28)
P value compared with Renal Failure0.72600.14280.2575
Grip strength (kg)Adjusted mean (SE)24.4 (1.7)36.2 (1.8)36.2 (0.8)38.0 (0.7)
P value compared with Renal Failure<0.0001<0.0001<0.0001
  • a The models are also adjusted for age, gender, race, and body mass index. The results were similar when adjusted for lean mass and percent fat.