Table 1.

Overview of study populations

Major ComorbidityTrial PopulationTrial Name
Renal failure, candidates for renal transplantation26 subjects age ≥60 yrPhysical Function and Quality of Life in Older Candidates for Kidney Transplantation
Diastolic heart failure71 subjects age ≥65 yrPharmacologic Intervention in the Elderly (PIE)
Chronic obstructive pulmonary disease176 subjects age 55 to 80 yrThe Reconditioning Exercise and Chronic Obstructive Pulmonary Disease Trial II (REACT II) (21)
High risk for cardiovascular disease294 subjects >55 to 80 yr of ageTrial of Angiotensin Converting Enzyme Inhibition and Novel
Cardiovascular Risk Factors (TRAIN) (22)