Table 2.

Clinical and laboratory characteristics of patients with and without coronary calcification (CAC)

CharacteristicWithout CACWith CACP
No. of patients (%)224 (57.7)164 (42.3)
Male gender (%)72.385.40.0022
Age > 65 yr old (%)4.929.90.0000
Diabetes mellitus (%)6.822.80.0001
GFR<60 ml/min (%)44.561.60.0009
Hypertension (%)78.692.00.0004
Pulse pressure ≥75th percentile (%)31.450.70.0003
Fibrinogen ≥75th percentile (%)19.032.70.01
hs-CRP ≥ 75th percentile (%)23.828.9NS
i-PTH above upper normal limit (%)39.639.3NS
Calcium above upper normal limit (%)38.143.2NS
Phosphorus above upper normal limit (%)22.316.3NS
Ca × P product above 55 mg2/dL2 (%)5.74.9NS
LDL-C above upper normal limit (%)67.658.2NS
Homocysteine ≥75th percentile (%)24.825.3NS
  • Fibrinogen 75th percentile value = 418 mg/dl; hs- CRP 75th percentile value = 0.4 mg/L; homocysteine 75th percentile value = 28.4 mg/L. Upper normal limit for i-PTH: 60 pg/ml for GFR ≥ 60 ml/min, 70 pg/ml for GFR range 59-30 ml/min, 110 pg/ml for GFR range 29-15 ml/min, and 300 pg/ml for GFR <15 ml/min. Upper normal limit for serum phosphorus: 4.6 mg/dl for GFR ≥15 ml/min and 5.5 mg/dl for GFR<15 ml/min. Upper normal limit for serum calcium:10.5 mg/dl for GFR ≥15 ml/min and 9.5 mg/dl for GFR <15 ml/min. LDL-C upper normal limit:100 mg/dl. GFR, glomerular filtration rate (as creatinine clearance); hs-CRP, high-sensitivity C-reactive protein; i-PTH, intact parathyroid hormone; Ca × P product, calcium–phosphorus product; LDL-C, low density lipoprotein-cholesterol.