Table 7.

Frequency of abnormal laboratory values and chart findings suggestive of TMA by renal pathology

FindingNDefinition 1 (n, %)aDefinition 2 (n, %)b
Pathology
    negative7118 (25)39 (55)
    TMA3011 (37)22 (73)
Isolated186 (33)14 (78)
Chart
    negative9927 (27)58 (59)
    positive168 (50)14 (88)
  • a Definition 1: hematocrit < 30, platelet count < 100,000, LDH above the upper limits of normal and a 50% increase in the baseline serum creatinine, in a single day's measurements.

  • b Definition 2: hematocrit < 30, platelet count < 100,000, LDH above the upper limits of normal, and a 50% increase in the serum baseline creatinine, each occurring at least once over the 2 wk measurements.