Table 2.

Pathologic findings in patients with very low birth weight-related FSGS

FindingPatient no.
123456
No. of glomeruli20329251412
No. of globally sclerotic glomeruli (%)6 (30)13 (41)1 (11)5 (20)3 (21)0
Tubular atrophy and fibrosis (% of cortex)15305202020
Glomerular diameter (μm; mean ± SD)241 ± 16248 ± 13254 ± 13216 ± 14257 ± 21207 ± 14
No. of segmentally sclerotic glomeruli (%)1 (5)2 (6)1 (11)4 (16)1 (7)1 (8)
Perihilar locationNoYesYesYesYesYes
Foot process effacement (%)30<25N/A303045
  • Patient 5 also had minimal mesangial glomerulonephritis consistent with IgA nephropathy (1+ mesangial IgA by immunofluorescence; no mesangial hypercellularity)