Table 3.

ΔCcr and ΔUF (baseline compared with 2 and 4 wk) grouped according to baseline PET transport characteristic group in ITT population

PET CategoryTimeΔCcr (ml/min)ΔUF (ml)
GLUICOP1GLUICOP2
High trspt2W0.16 ± 0.140.98 ± 0.180.0003−67.6 ± 59.2495.6 ± 77.2<0.0001
(n = 24)4W−0.17 ± 0.180.75 ± 0.230.001417.7 ± 61. 4456.3 ± 79.0<0.0001
HA trspt2W0.19 ± 0.090.82 ± 0.09<0.000137.5 ± 37.1428.3 ± 36.4<0.0001
(n = 72)4W−0.02 ± 0.120.78 ± 0.11<0.000113.0 ± 39.0439.3 ± 39.0<0.0001
LA trspt2W0.15 ± 0.080.55 ± 0.090.000884.3 ± 33.9221.8 ± 38.90.0046
(n = 81)4W0.21 ± 0.100.55 ± 0.120.024100.5 ± 35.5269.7 ± 41.40.0009
L trspt2W0.23 ± 0.200.43 ± 0.140.40188.6 ± 82.3216.2 ± 58.30.77
(n = 21)4W−0.11 ± 0.250.28 ± 0.180.20162.8 ± 85.0134.5 ± 62.70.78
  • ΔUF, UF of long dwell in wk 2/wk 4–UF of long dwell in baseline; ΔCcr, Ccr of long dwell in wk 2/wk 4–Ccr of long dwell in baseline.