Table 5.

Multivariate Cox regression analysis of risk factors at baseline for all-cause mortality—log-normalized serum IS level entered as a continuous variable

Models of Patient Survival (event n = 25)RRa95% CIP
Unadjusted (GF = 18; P < 0.0001)2.3911.551 to 3.684<0.0001
Model 1a (GF = 32; P < 0.0001)2.4681.617 to 3.767<0.0001
Model 2b (GF = 25; P < 0.0001)2.1051.373 to 3.2260.001
Model 3c (GF = 29; P < 0.0001)2.1651.377 to 3.4020.001
Model 4d (GF = 19; P < 0.0001)2.2261.363 to 3.6370.001
  • Summarizing the risk of a 1-SD (1.076) increment in log-normalized serum IS level for unadjusted model and for noncumulative models adjusted for multiple variables.

  • a Model 1 was adjusted for age (in decades), diabetes status, and male gender.

  • b Model 2 was adjusted for serum albumin (in 1-g/L increments), hemoglobin (in 1-g/L increments), and phosphate (in 1-mMol/L increments) levels.

  • c Model 3 was adjusted for the aortic calcification score on computed tomography (in 1% increments) and PWV (in 1-m/s increments).

  • d Model 4 was adjusted for the aortic calcification score on x-ray (in 1-unit increments).