Table 1.

Demographics, medical history, and key baseline laboratory values

CharacteristicCinacalcet-D (n = 87)Flex-D (n = 86)
Male/female, n (%)52/35 (60/40)45/41 (52/48)
Age, mean (SD), years57.7 (14.9)59.0 (12.4)
Time on dialysis, mean (SD), months46.3 (36.4)46.8 (44.1)
Medical history, positive, n (%)a
    diabetes49 (56)61 (71)
    hypertension81 (93)86 (100)
    peripheral vascular disease18 (21)22 (26)
    cerebrovascular accident11 (13)14 (16)
    myocardial infarction10 (11)18 (21)
    coronary artery disease29 (33)36 (42)
    congestive heart failure26 (30)32 (37)
iPTH, median (Q1,Q3), pg/ml
    pre-washout414 (316, 550)428 (328, 553)
    baseline597 (471, 775)621 (463, 833)
Serum calcium, median (Q1,Q3), mg/dl
    pre-washout9.8 (9.5, 10.3)10.0 (9.5, 10.5)
    baseline9.6 (9.2, 10.0)9.7 (9.4, 10.0)
Serum phosphorus, median (Q1,Q3), mg/dl
    pre-washout5.9 (4.5, 7.0)5.4 (4.8, 6.2)
    baseline5.1 (4.2, 6.4)5.2 (4.1, 5.9)
Ca×P, median (Q1,Q3), mg2/dl2
    pre-washout56.8 (44.7, 67.6)53.6 (46.6, 61.6)
    baseline48.9 (39.4, 59.4)49.0 (40.2, 56.7)
Vitamin D at pre-washout, μg/wkb
    median (Q1,Q3)13.5 (9.0, 21.0)15.0 (12.0, 24.0)
    mean (SD)16.7 (11.8)18.7 (11.3)
  • SD, standard deviation; iPTH, intact parathyroid hormone; Q1, first quartile; Q3, third quartile; Ca×P, calcium-phosphorus product.

  • a Subjects could have multiple comorbidities.

  • b Data not available for 2 subjects in the Cinacalcet-D group and 1 subject in Flex-D group.