Table 3.

Adjusted IRR for all infectious events for subgroups of patients by baseline phosphate level

SubgroupaIRR (95% CI) versus 3.5 to 5.5 mg/dlb
<3.5 mg/dl>5.5 mg/dl
Age (yr)
    <65 (n = 601)0.90 (0.60 to 1.35)1.43 (1.21 to 1.68)c
    ≥65 (n = 329)0.47 (0.30 to 0.74)c0.95 (0.75 to 1.21)
    Pinteraction0.010c0.008c
Race
    white (n = 619)0.63 (0.40 to 1.00)1.25 (1.05 to 1.47)c
    black (n = 257)0.49 (0.32 to 0.74)c1.02 (0.78 to 1.32)
    Pinteraction0.8050.799
Diabetic status
    nondiabetic (n = 424)0.83 (0.55 to 1.25)1.51 (1.20 to 1.89)c
    diabetic (n = 499)0.44 (0.30 to 0.71)c1.18 (1.00 to 1.40)c
    Pinteraction0.040c0.422
BMI (kg/m2)
    <25 (n = 366)0.72 (0.52 to 0.99)c1.29 (1.09 to 1.53)c
    ≥25 (n = 490)0.84 (0.64 to 1.11)1.23 (1.08 to 1.39)c
    Pinteraction0.2450.791
Albumin (g/dl)
    <3.7 (n = 482)0.89 (0.70 to 1.13)1.29 (1.14 to 1.47)c
    ≥3.7 (n = 447)0.46 (0.32 to 0.67)c1.22 (1.05 to 1.40)c
    Pinteraction0.013c0.369
Creatinine (g/dl)
    <7.0 (n = 469)0.56 (0.42 to 0.74)c1.46 (1.28 to 1.66)c
    ≥7.0 (n = 459)1.61 (1.21 to 2.14)c1.17 (1.03 to 1.33)c
    Pinteraction0.3170.732
Dialysis dose (hemodialysis only)
    Kt/V <1.3 (n = 308)1.08 (0.77 to 1.51)0.98 (0.83 to 1.16)
    Kt/V ≥1.3 (n = 245)0.88 (0.56 to 1.38)1.49 (1.23 to 1.80)c
    Pinteraction0.2700.009c
  • a Observations in groups with no variation in outcome dropped in conditional modeling.

  • b Adjusted for demographics (age, gender, race), clinical (modality, ICED, smoking status), and laboratory (albumin, creatinine, hemoglobin).

  • c P < 0.05.