Table 1.

Baseline characteristics of groups treated with monotherapy and combined therapya

CharacteristicGroup C (n = 35)Group M (n = 20)Pb
Age (yr; mean ± SD)30.9 ± 12.327.0 ± 10.70.362
Gender (M/F)11/2410/100.173
Presence of macroscopic hematuria (n [%])16 (45.7)8 (40.0)0.681
SBP (mmHg; mean ± SD)122.0 ± 12.9127.6 ± 16.60.169
DBP (mmHg; mean ± SD)73.1 ± 11.776.3 ± 11.90.344
    patients with >140/90 mmHg (n [%])5 (14.3)6 (30.0)0.147
UOB score (mean ± SD)2.17 ± 0.862.40 ± 0.750.352
UP score (mean ± SD)2.17 ± 0.792.35 ± 0.750.412
Proteinuria (g/d; mean ± SD)1.06 ± 1.011.41 ± 1.050.136
    patients with UP >1.0 g/d (n [%])13 (37.1)12 (60.0)0.101
Serum creatinine (mg/dl; mean ± SD)0.72 ± 0.290.84 ± 0.300.142
    patients with sCr >1.2 mg/dl (n [%])3 (8.6)3 (15.0)0.377
Creatinine clearance (ml/min; mean ± SD)96.7 ± 33.695.6 ± 34.70.806
    patients with Ccr <60 ml/min (n [%])3 (8.6)2 (10.0)0.752
Serum uric acid (mg/dl; mean ± SD)5.36 ± 1.245.98 ± 1.520.128
Serum total cholesterol (mg/dl; mean ± SD)202.2 ± 45.4208.8 ± 52.10.643
Serum IgA (mean ± SD)317.9 ± 125.0326.5 ± 108.40.694
Serum C3 (mean ± SD)94.5 ± 19.391.0 ± 23.90.549
Histologic gradec0.217
    100
    2133
    31915
    432
  • a DBP, diastolic BP; Group C, combined therapy (steroid pulse with tonsillectomy); group M, monotherapy (steroid pulse); SBP, systolic BP; UOB, urinary occult blood; UP, urinary protein.

  • b Data compared using Mann-Whitney U test, unpaired t test, and χ2 test.

  • c Histologic grading in both groups compared using Pearson χ2 test.