Table 1.

Characteristics of participants with and without prevalent subclinical hypothyroidism (n = 3089)

Subclinical Hypothyroidism (n = 293)No Hypothyroidism (n = 2796)P
Age (yr)57.9 ± 17.353.2 ± 17.5<0.0001
Women [N (%)]228 (77.8%)2179 (77.9%)0.90
TSH (mIU/L)8.19 ± 5.721.69 ± 1.01<0.0001
Free T4 (ng/dl)1.2 ± 0.21.3 ± 0.2<0.0001
Fasting glucose (mg/dl)105 ± 2092 ± 16<0.0001
Total cholesterol (mg/dl)209 ± 50189 ± 43<0.0001
Triglycerides (mg/dl)124 ± 89108 ± 53<0.0001
Estimated GFR (ml/min per 1.73 m2)79.7 ± 40.786.6 ± 32.2<0.001
    ≥9076 (25.9%)995 (35.6%)<0.0001
    60-89169 (57.8%)1572 (56.2%)
    30-5947 (16.0%)218 (7.8%)
    <301 (0.3%)11 (0.4%)
  • Values are mean ± SD or number or proportions. Differences between groups are assessed by the unpaired t test (for continuous variables) and the χ2 test (for categorical variables). TSH, thyrotropin; T4, thyroxine; GFR, glomerular filtration rate.