Multiple regression models showing association of ACEI/ARB with AKIa
| Variable | Point Estimate | 95% CI |
|---|---|---|
| Model 1: Logistic model for AKI by ACEI/ARBb | ||
| demographics | 1.51 | 1.200 to 1.910 |
| demographics + diabetes | 1.39 | 1.100 to 1.760 |
| demographic + diabetes + CHF | 1.28 | 1.010 to 1.640 |
| Model 2: All variables that were significant in univariate model + demographics, NSAID | ||
| ACEI/ARB | 1.35 | 1.050 to 1.730 |
| age | 1.04 | 1.030 to 1.060 |
| NSAID (not used) | 0.77 | 0.530 to 1.140 |
| diabetes | 1.66 | 1.290 to 2.130 |
| CABG + valve replacement | 2.24 | 1.590 to 3.160 |
| emergency surgery | 1.49 | 0.990 to 2.230 |
| CHF | 1.42 | 1.050 to 1.910 |
| intraoperative hypotension | 1.36 | 1.060 to 1.740 |
| on pump | 1.89 | 1.440 to 2.480 |
| intraoperative IVF (L) | 1.06 | 1.004 to 1.130 |
| Model 3: Logistic model after matching on propensity score | ||
| ACEI/ARB | 1.41 | 1.070 to 1.850 |
| age | 1.04 | 1.030 to 1.050 |
| NSAID | 0.80 | 0.490 to 1.290 |
| diabetes | 1.66 | 1.290 to 2.130 |
| CABG + valve replacement | 1.69 | 1.230 to 2.590 |
| emergency surgery | 1.21 | 0.750 to 1.940 |
| CHF | 1.34 | 0.930 to 1.940 |
| intraoperative hypotension | 1.42 | 1.060 to 1.880 |
| on pump | 1.89 | 1.380 to 2.590 |
| intraoperative IVF (L) | 1.05 | 0.980 to 1.130 |