Characteristics of patients with diabetic nephropathy enrolled in study Ba
| Characteristic | Overall | Deficiency (<15 ng/ml) | Insufficiency (15 to 30 ng/ml) | Optimal (>30 ng/ml) | P |
|---|---|---|---|---|---|
| n | 146 | 55 | 66 | 25 | |
| Age (yr) | 57.0 ± 0.6 | 54.0 ± 0.9 | 57.5 ± 0.8 | 62.5 ± 1.8 | <0.001 |
| Male gender (%) | 51 | 40 | 59 | 52 | 0.110 |
| Race/ethnicity (%) | |||||
| Latino | 77 | 66 | 82 | 88 | 0.002 |
| black | 10 | 24 | 3 | 0 | |
| white | 13 | 11 | 15 | 12 | |
| Serum creatinine (mg/dl)b | 1.3 (1.0, 1.8) | 1.6 (1.1, 2.1) | 1.3 (1.0, 1.8) | 1.0 (0.8, 1.5) | 0.003 |
| eGFR (ml/min per 1.73 m2) | 55.4 ± 2.1 | 47.9 ± 23.8 | 57.3 ± 2.9 | 66.8 ± 5.1 | 0.004 |
| Urine albumin-to-creatinine ratio (mg/mg)b | 1.99 (0.79, 3.93) | 3.02 (0.85, 4.31) | 2.05 (0.97, 3.77) | 0.91 (0.58, 2.21) | 0.020 |
| Diabetes duration (yr) | 15.3 ± 0.5 | 16.7 ± 0.9 | 14.3 ± 0.7 | 15.2 ± 1.2 | 0.110 |
| Current smokers (%) | 13 | 9 | 15 | 16 | 0.550 |
| Hypertension (%) | 95 | 96 | 91 | 100 | 0.180 |
| Dyslipidemia (%) | 84 | 82 | 86 | 84 | 0.790 |
| BMI (kg/m2) | 31.2 ± 0.6 | 32.7 ± 1.0 | 30.7 ± 1.0 | 29.2 ± 1.1 | 0.110 |
| Serum CRPb | 0.4 (0.1, 0.8) | 0.5 (0.1, 0.9) | 0.4 (0.1, 0.9) | 0.2 (0.1, 0.5) | 0.200 |
| HbA1c (%) | 8.6 ± 0.2 | 8.3 ± 0.4 | 8.7 ± 0.3 | 9.1 ± 0.4 | 0.350 |
| Serum albumin (g/dl) | 3.2 ± 0.1 | 3.1 ± 0.1 | 3.3 ± 0.1 | 3.5 ± 0.1 | 0.002 |
| Corrected serum calcium (mg/dl) | 9.8 ± 0.0 | 9.7 ± 0.1 | 9.8 ± 0.1 | 9.8 ± 0.1 | 0.630 |
| Serum phosphorus (mg/dl) | 4.3 ± 0.1 | 4.4 ± 0.1 | 4.3 ± 0.1 | 4.2 ± 0.1 | 0.310 |
| Serum PTH (pg/ml)b | 51 (32, 79) | 61 (40, 112) | 45 (31, 67) | 40 (22, 55) | <0.001 |
| BMD (mg/cm3) | 130.2 ± 4.3 | 143.4 ± 6.2 | 127.0 ± 7.0 | 108.3 ± 8.3 | 0.020 |
| Prevalence of T score <−1.0 (%) | 64 | 56 | 66 | 79 | |
| Coronary artery calcification | |||||
| Prevalence (score >10) (%) | 75 | 58 | 83 | 88 | 0.002 |
| scoreb | 149 (9, 488) | 85 (0, 325) | 200 (25, 637) | 196 (59, 370) | 0.040 |