Table 1.

Patient demographics and baseline laboratory values

CharacteristicaConventional Care (n = 184)Cinacalcet (n = 368)
Sex, n (%)
    male117 (64)224 (61)
    female67 (36)144 (39)
Race, n (%)b
    white172 (93)349 (95)
    black and other12 (7)14 (3)
Age, years
    mean (SD)58.3 (14.5)58.5 (14.5)
    range24 to 8420 to 89
Duration of dialysis, months mean (SD)69.4 (73.6)64.1 (72.1)
Dialysis type, n (%)
    hemodialysis151 (82)285 (77)
    hemodiafiltration28 (15)59 (16)
    hemofiltration03 (1)
    peritoneal dialysis5 (3)21 (6)
Vitamin D use, n (%)126 (68)252 (68)
Phosphate binder use, %9092
    calcium-based4148
    sevelamer HCl5452
    aluminum-based2019
iPTH, mean (SD), pg/ml507 (143)505 (147)
Ca × P, mean (SD) mg2/dl252.5 (15.4)53.6 (16.4)
    ≤55 mg2/dl2, n (%)113 (61)227 (62)
    >55 mg2/dl2, n (%)71 (39)141 (38)
Serum calcium, mean (SD), mg/dl9.7 (0.8)9.7 (0.8)
Serum phosphorus, mean (SD), mg/dl5.4 (1.5)5.5 (1.7)
  • a No statistically significant differences between the two groups in any baseline demographic or laboratory value comparison.

  • b Race information was lacking for five patients in the cinacalcet group.