Table 2.

Randomized trials of oral fluid/solute supplementation

StudyNo. of PatientsOral Volume RegimenIntravenous Fluid RegimenBaseline SCr (mg/dl)Rate of CIN (Oral versus Intravenous)P
Taylor et al. (40)361000 ml of H2O for 10 ha0.45% NaCl 75 ml/h for 24 h1.74 to 1.756 versus 11%NS
Trivedi et al. (13)53Unrestricted oral fluids0.9% NaCl 1 ml/kg per h for 24 h1.14 to 1.2734.6 versus 3.7%0.005
Dussol et al. (39)3531 g/10 kg per d NaCl for 2 d0.9% NaCl 15 ml/kg for 6 h2.15 to 2.426.6 versus 5.2%NS
  • a Included 300 ml of intravenous 0.45% NaCl begun 30 to 60 min before radiocontrast administration and continued for 6 h.