Table 4.

Full model and final model for hemoglobin variation

ParameterModel with All ParametersFinal Model
Coef.95% CIPCoef.95% CIP
Epo dose (per 10,000 units/month)−0.18−0.28 to −0.09<0.0001−0.18−0.26 to −0.10<0.0001
Epo dose × time0.050.01 to 0.100.010.040.01 to 0.07<0.01
Serum albumin (g/dl)0.780.15 to 1.410.020.730.18 to 1.280.01
Albumin × time0.410.03 to 0.790.030.490.14 to 0.84<0.01
WBC count (n/1000/ml)0.120.01 to 0.230.03
Iron dose (per 100 mg/month)−0.04−0.13 to 0.040.3
Iron dose × time0−0.00 to 0.000.1
Post dialysis weight (kg)−0.01−0.03 to 0.000.1
WBC count × time−0.03−0.08 to 0.020.2
Plasma malonaldehyde (mmol/L)0.02−0.09 to 0.130.7
Malonaldehyde × time0.01−0.04 to 0.070.6
log Plasma MCP1 (ng/ml)0.07−0.31 to 0.450.7
log Plasma MCP1 × time−0.14−0.32 to 0.050.2
Serum iron0−0.00 to 0.000.5
Serum iron × time0−0.00 to 0.000.7
Log serum ferritin−0.31−0.69 to 0.060.1
Log ferritin × time0.1−0.02 to 0.220.1
Total iron binding capacity0−0.01 to 0.010.9
Total iron binding capacity × time0−0.00 to 0.000.9
Constant14.8211.40 to 18.23<0.000112.612.2 to 13.0<0.0001
Random Effects
    SD Intercept0.61.53
        SD Time1.630.59
    Corr (intercept, time)−0.49−0.46
    SD Residual0.760.84
        LL−442−519.8
  • Albumin is centered at 4 g/dl and white blood cell (WBC) count at 4000/μl.