Table 7.

Recommended dosage of fomepizole for patients with methanol and ethylene glycol intoxicationa

Without dialysis
    Loading dose
        15 mg/kg body wt
    Maintenance dose
        10 mg/kg body wt every 12 h for 4
        15 mg/kg/ body wt every 12 h (if blood levels do not reach goal by 48 h)
With dialysis
    Add 1 to 1.5 mg/kg body wt per h
  • a Dosage may have to be adjusted if <6 h from last dose. Protocol theoretically used for treatment of other intoxications. Reprinted from reference (12), with permission.