Table 3.

Baseline histologic featuresa

ParameterCRPRNRP
n372128
WHO III ≥50% (n [%])14 (38)12 (57)18 (64)0.07
WHO IV (n [%])23 (62)8 (38)10 (36)
Unclassified (n [%])1 (5)
Activity index (mean ± SD)11.8 ± 4.211.2 ± 5.412.7 ± 4.6NS
    ≥12 (n [%])16 (43)10 (48)16 (57)NS
Chronicity index (mean ± SD)2.3 ± 1.84.1 ± 2.54.4 ± 2.80.001b
    ≥4 (n [%])10 (27)14 (67)17 (61)0.003c

  • ↵a WHO, World Health Organization.

  • ↵b P < 0.01, CR versus NR; P < 0.05, CR versus PR.

  • ↵c P < 0.01, CR versus NR; P < 0.005, CR versus PR.