Table 2.

Tobramycin dose administered and the resultant serum tobramycin concentrationsa

PatientDosage(mg; 1.5 mg/kg)Measured Serum Tobramycin Concentrations (mg/L)
Conventional MethodStudy Method
Before Drug Infusion (Control)1 h after InfusionBefore Next HDBefore Start of HD (Control)1 h after InfusionEnd of HDBefore Next HD
115006.12.602.50.30.1
216005.11.702.30.30.1
314005.72.603.10.60.3
412006.62.802.30.20.1
516505.12.502.60.50.2
Average ± SD147 ± 17.8905.83 ± 0.672.44 ± 0.4302.56 ± 0.330.38 ± 0.160.2 ± 0.1
  • a HD, hemodialysis.