Table 1.

Baseline characteristics according to eGFRa

CharacteristiceGFR (ml/min per 1.73 m2)
<60 (n = 600)≥60 (n = 2638)
Age (yr)76.7 ± 5.873.9 ± 4.8
Male34 (204)39 (1021)
Race
    white85 (509)82 (2161)
    black14 (83)18 (468)
    other1.3 (8)0.3 (9)
Diabetes status
    normal77 (459)77 (2022)
    impaired fasting glucose12 (71)10 (258)
    diabetes11 (70)13 (358)
Smoker status
    never smoked48 (287)46 (1216)
    former smoker42 (250)42 (1093)
    current smoker9 (53)11 (282)
Alcohol use
    none59 (354)53 (1387)
    1 to 7 drinks/wk33 (198)35 (930)
    >7 drinks/wk8 (47)12 (316)
Medication use
    digoxin4 (22)3 (81)
    β blocker11 (68)7 (193)
    calcium channel blocker13 (76)11 (297)
    thiazide diuretic25 (151)15 (403)
    potassium-sparing diuretic15 (87)6 (161)
    loop diuretic7 (43)3 (76)
    ACE inhibitor13 (77)8 (217)
    aspirin33 (196)30 (792)
SBP (mmHg)138.0 ± 22.2136.0 ± 20.8
Weight (lb)159.0 ± 33.4159.0 ± 32.2
Laboratory values
    creatinine (mg/dl)1.3 ± 0.550.9 ± 0.18
    cystatin C (mg/L)1.4 ± 0.441.0 ± 0.18
    eGFR (ml/min per 1.73 m2)51.1 ± 8.7683.6 ± 16.4
    potassium (mEq/L)4.2 ± 0.454.1 ± 0.38
    albumin (g/dl)3.9 ± 0.273.9 ± 0.27
    hemoglobin (g/dl)13.3 ± 1.4213.8 ± 1.4
    total cholesterol (mg/dl)214.0 ± 39.0209.0 ± 37.1
    HDL cholesterol (mg/dl)52.9 ± 14.454.9 ± 14.6
  • a Data are % (n) or means ± SD. ACE, angiotensin-converting enzyme; eGFR, estimated GFR; SBP, systolic BP.