Table 4.

Blood and urine biochemical data in patient groupsa

Group (n)CCr (ml/min per 1.73)PK (mmol/L)PCl (mmol/L)PHCO3 (mmol/L)PMg (mg/dl)Prenin (Ratio)bPaldo (Ratio)bUNaV (mmol/d)UClV (mmol/d)UMgV (mg/d)UCa/UCr (mg/mg)
GSad (22)100 ± 222.6 ± 0.397 ± 330.9 ± 3.81.4 ± 0.3c3.2 ± 2.71.4 ± 1.4227 ± 109d240 ± 144e89 ± 350.06 ± 0.05
GSa-c (19)132 ± 292.7 ± 0.396 ± 229.4 ± 2.61.6 ± 0.3c3.8 ± 2.11.3 ± 1.0153 ± 66150 ± 7890 ± 470.04 ± 0.02
BS (7)106 ± 332.5 ± 0.2100 ± 429.7 ± 4.32.0 ± 0.43.1 ± 1.91.8 ± 0.698 ± 81142 ± 8166 ± 250.46 ± 0.36d
PB (3)60 ± 31f2.6 ± 0.391 ± 4f32.7 ± 5.42.1 ± 0.45.4 ± 4.415.3 ± 19.4117 ± 112183 ± 22731 ± 6g0.13 ± 0.04g
n/range>803.5 to 4.595 to 11022 to 281.6 to 2.2<1<1Dietary intakehDietary intakeh25 to 1800.03 to 0.20
  • a Data are means ± SD. aldo, aldosterone; BS, Bartter syndrome; CCr, creatinine clearance; GSa-c, Gitelman syndrome in children-adolescents; GSad, Gitleman syndrome in adults; PX, plasma levels of X; PB, nontubular hypokalemia; UX/VX, urine excretion of X; UCa/UCr, ratio between calcium and creatinine excretion.

  • b The ratio between individual values and maximal normal level for the assay.

  • c P < 0.01 versus BS and PB.

  • d P < 0.01 versus all other groups.

  • e P < 0.02 versus GSa-c and BS.

  • f P < 0.05 versus all other groups.

  • g P < 0.02 versus GSad and GSa-c.

  • h In our adult population: 60 to 380 mmol/d.