Table 2.

CHr in the assessment of iron statusa

StudyStandardOther ComparisonsSensitivitySpecificity
Mittman et al. (7)Functional (1% ↑ in corrected reticulocyte index after intravenous iron 500 mg)Serum ferritin < 100 ng/mlTSAT < 20%CHr 78%serum ferritin 38%TSAT 50%CHr 71%serum ferritin 53%TSAT 60%
Chuang et al. (8)Functional (30% ↓ in EPO dose after intravenous iron 2200 mg over 24 wk)Serum ferritin < 300 ng/mlCHr 78%serum ferritin 83%CHr 87%serum ferritin 57%
  • a CHr, reticulocyte hemoglobin (Hb) content; EPO, erythropoietin.