Table 3.

Pathologic diagnoses for protocol biopsies (performed in the setting of stable graft function at different time points after transplantation for surveillance)a

Biopsy Diagnosis3 Mo6 Mo12 Mo24 MoTotal% Biopsies
CNITb171818146740.9
CAN181515105835.7
Acute rejectionb011021.3
Acute rejection + CNIT000110.6
No significant abnormality7212127.3
Other (reflux, ATN, GN, etc.)013263.7
Inadequate47431811
Total46444232164100
  • a More than two thirds of the biopsies have chronic injury from CNIT or other undefined causes of CAN. Fewer than 10% of biopsies are completely normal at 2-yr follow-up.

  • b Does not include cases with both features of CNIT and acute rejection.