Table 1.

Calculation of CNIT score based on six histologic features of CNITa

Histologic FeatureExtentScore (0 to 3)
Tubular isometricNone0
    vacuoles1 to 25%1
26 to 50%2
>50%3
Interstitial fibrosis0 to 5%0
6 to 25%1
26 to 50%2
>50%3
Arteriolar medialNone0
    hyalinosis10% or fewer arterioles1
11 to 30% of arterioles2
>30% arterioles3
GlomerulosclerosisNone0
1 to 25%1
26 to 50%2
>50%3
Tubular atrophyNone0
1 to 25%1
26 to 50%2
>50%3
Mesangial matrixNone0
    increase1 to 25%1
26 to 50%2
>50%3
Total score18
  • a CNIT, calcineurin inhibitor toxicity.