Table 6.

Immunohistologic scores of coronary arteries

ParameterNonrenal (n = 11)Nonrenal, Calcified (n = 13)Uremia (n = 12)Uremia, Calcified (n = 12)P (ANOVA)
CRP
    intima0.2 ± 0.120.23 ± 0.160.53 ± 0.14a0.3 ± 0.09<0.005
    media0.27 ± 0.080.38 ± 0.190.59 ± 0.42a0.38 ± 0.01<0.05
PTX3
    intima0.19 ± 0.090.43 ± 0.270.53 ± 0.270.53 ± 0.27<0.05
    media0.33 ± 0.060.41 ± 0.20.6 ± 0.260.6 ± 0.26<0.05
Fetuin A
    intima0.95 ± 0.52.03 ± 0.70.53 ± 0.10.77 ± 0.5b<0.001
    media1.43 ± 0.52.2 ± 0.31.1 ± 0.21.3 ± 0.6b<0.05
HIF-1α
    intima0.63 ± 0.50.38 ± 0.341.34 ± 0.47a0.86 ± 0.38<0.05
    media0.93 ± 0.220.90 ± 0.41.42 ± 0.611.28 ± 0.38NS
C5b-9
    intima0.31 ± 0.11.9 ± 0.1c0.46 ± 0.32.53 ± 0.1d<0.05
    media0.04 ± 0.050.2 ± 0.04c0.2 ± 0.20.6 ± 0.1d<0.05
Collagen IV
    intima0.3 ± 0.10.4 ± 0.440.91 ± 0.3a0.3 ± 0.19<0.05
    media0.4 ± 0.150.4 ± 0.30.77 ± 0.12a0.29 ± 0.21<0.05
TGF-β
    intima0.06 ± 0.010.06 ± 0.0080.49 ± 0.26a0.2 ± 0.14b<0.05
    media0.06 ± 0.010.06 ± 0.0080.49 ± 0.26a0.2 ± 0.14b<0.05
ET-1
    intima0.03 ± 0.01a,c0.59 ± 0.20.3 ± 0.1d0.89 ± 0.2<0.05
    media0.05 ± 0.1a,c0.99 ± 0.30.5 ± 0.30.94 ± 0.2<0.05
vWF
    intima0.94 ± 0.61.42 ± 0.22.02 ± 0.5a1.96 ± 0.9<0.001
    media0.89 ± 0.31.8 ± 0.21.7 ± 0.4a1.9 ± 0.4<0.05
eNOS
    intima0.08 ± 0.01a0.1 ± 0.40.4 ± 0.020.22 ± 0.01<0.05
    media0.02 ± 0.01a,c0.2 ± 0.30.6 ± 0.30.2 ± 0.4<0.05
Glycophorin A
    intima0a,c0.14 ± 0.010.82 ± 0.060.64 ± 0.03<0.001
    media0000NS
CD68
    intima0b2.15 ± 1.05c0.8 ± 0.25.75 ± 3.32a<0.05
    media1.1 ± 0.2b2.21 ± 0.75c7.5 ± 4.825.08 ± 4.89a<0.05
  • P < 0.05:

  • a control versus renal,

  • b control calcified versus renal calcified,

  • c control versus calcified controls,

  • d renal versus calcified renal.