Table 4.

Linear multiple regression between age, gender, and hypertension to parametersa

Parameterβ95% CIP
Media thickness
    age0.1790.216 to 1.000.003
    gender0.0680.009 to 0.0710.666
    hypertension0.1900.048 to 0.1890.234
Intima thickness
    age0.0680.022 to 0.0140.658
    gender0.0410.303 to 0.2330.792
    hypertension0.3020.011 to 0.6930.057
Media area
    age0.2040.01 to 0.0540.181
    gender0.0840.609 to 0.3460.581
    hypertension0.1910.238 to 1.0250.215
Intima area
    age0.1020.01 to 0.0540.512
    gender0.10.609 to 0.3460.524
    hypertension0.10.238 to 1.0250.523
Plaque area
    age0.3080.002 to 0.0410.032
    gender0.0750.216 to 0.370.598
    hypertension0.2740.014 to 0.7620.058
Lumen area
    age0.1830.178 to 0.0410.214
    gender0.0351.437 to 1.8270.811
    hypertension0.3580.440 to 4.7580.019
Lumen area/lumen + intima
    age0.070.005 to 0.0080.638
    gender0.0550.077 to 0.1110.715
    hypertension0.3660.275 to −0.270.018
CRP intima
    age0.0970.025 to 0.0130.525
    gender0.0190.299 to 0.2650.904
    hypertension0.2620.058 to 0.6870.096
    calcification0.3350.513 to −0.0970.005
    renal insufficiency0.5960.336 to 0.7530.0001
CRP media
    age0.1140.008 to 0.1080.429
    gender0.1270.275 to 0.1080.385
    hypertension0.3890.083 to 0.590.01
    age0.3450.389 to −0.0640.007
    gender0.4990.166 to 0.4920.0001
PTX3 intima
    age0.0860.008 to 0.0160.538
    gender0.4170.441 to −0.0850.005
    hypertension0.3130.025 to 0.4960.031
PTX3 media
    age0.2640.022 to 0.0020.86
    gender0.00.175 to 0.1751
    hypertension0.1820.094 to 0.3680.238
Fetuin A intima
    age0.0190.031 to 0.0350.9
    gender0.1220.691 to 0.2910.416
    hypertension0.3031.303 to −0.0040.049
    calcification0.4980.481 to 1.1470.0001
    renal insufficiency0.5821.288 to −0.620.0001
Fetuin A media
    age0.0490.038 to 0.0270.738
    gender0.1710.770 to 0.2030.246
    hypertension0.3081.314 to −0.0270.041
    calcification0.30.099 to 0.8910.016
    renal insufficiency0.5641.333 to −0.5380.0001
HIF-1α intima
    age0.0070.022 to 0.0210.962
    gender0.0910.411 to 0.2180.541
    hypertension0.3790.112 to 0.9440.014
HIF-1α media
    age0.1190.01 to 0.0250.422
    gender0.0350.23 to 0.2910.814
    hypertension0.3150.018 to 0.7060.04
C5b-9 intima
    age0.0010.041 to 0.0410.993
    gender0.0040.605 to 0.6220.978
    hypertension0.1070.54 to 1.0830.503
C5b-9 media
    age0.0280.032 to 0.0270.854
    gender0.090.31 to 0.5580.567
    hypertension0.1840.910 to 0.2390.245
Collagen IV intima
    age0.1110.02 to 0.0090.466
    gender0.1950.36 to 0.0810.208
    hypertension0.20.103 to 0.480.2
Collagen IV media
    age0.1090.018 to 0.0090.488
    gender0.0440.221 to 0.1670.78
    hypertension0.1160.163 to 0.350.467
TGF-β intima
    age0.1420.022 to 0.0080.34
    gender0.0070.215 to 0.2250.963
    hypertension0.3420.04 to 0.6230.027
TGF-β media
    age0.1480.024 to 0.0080.327
    gender0.0110.25 to 0.2330.943
    hypertension0.3460.042 to 0.6770.027
ET-1 intima
    age0.1090.021 to 0.010.468
    gender0.0330.254 to 0.2040.829
    hypertension0.3610.055 to 0.6570.022
ET-1 media
    age0.1110.025 to 0.0120.482
    gender0.0120.265 to 0.2860.937
    hypertension0.1680.173 to 0.5520.298
vWF intima
    age0.1160.018 to 0.0420.423
    gender0.0510.367 to 0.520.729
    hypertension0.3490.108 to 1.2810.021
vWF media
    age0.0010.03 to 0.030.993
    gender0.0340.492 to 0.3920.822
    hypertension0.3650.127 to 1.2970.018
eNOS intima
    age0.2420.015 to 0.0010.095
    gender0.0390.136 to 0.1040.789
    hypertension0.40.06 to 0.3780.008
eNOS media
    age0.0140.01 to 0.010.925
    gender0.090.193 to 0.1050.556
    hypertension0.3070 to 0.3950.05
Glycophorin A intima
    age0.0130.102 to 0.0930.93
    gender0.0831.852 to 1.0540.582
    hypertension0.3370.215 to 4.0590.03
CD68 intima
    age0.0540.094 to 0.1340.728
    gender0.1480.909 to 2.5180.349
    hypertension0.1401.262 to 3.2460.379
CD68 media
    age0.0830.585 to 0.3330.582
    gender0.0467.923 to 5.8350.761
    hypertension0.3541.737 to 19.8370.021
Intima calcium
    age0.0360.444 to 0.3580.828
    gender0.0335.526 to 6.7270.844
    hypertension0.0198.295 to 7.4380.913
Intima phosphorus
    age0.1770.338 to 0.1030.288
    gender0.0572.774 to 3.9180.731
    hypertension0.1033.134 to 5.890.54
Media calcium
    age0.0610.429 to 0.2890.695
    gender0.2159.173 to 1.7930.181
    hypertension0.2950.596 to 13.4850.072
Media phosphorus
    age0.0510.09 to 0.1230.759
    gender0.1182.185 to 1.0460.479
    hypertension0.1271.365 to 2.9910.454
CRP in situ hybridization intima
    age0.1150.058 to 0.250.423
    gender0.1840.246 to 1.0490.216
    hypertension0.1111.193 to 0.6060.510
    calcification0.5270.538 to 1.760.001
    renal insufficiency0.3330.002 to 1.4540.049
CRP in situ hybridization media
    age0.0560.058 to 0.250.704
    gender0.0720.246 to 1.0490.630
    hypertension0.0171.193 to 0.6060.919
    calcification0.5170.538 to 1.760.001
    renal insufficiency0.330.002 to 1.4540.056
  • a CI, confidence interval; CRP, C-reactive protein; eNOS, endothelial nitric oxide synthase; ET-1, endothelin-1; HIF-1α, hypoxia-inducible factor-1α; vWF, von Willebrand factor.