Table 1.

Inclusion criteriaa

1. New patients with WG, MPA, CSS, or RLV, with or without histologic confirmationb
2. Renal involvementc with or without other organ involvements, attributable to active WG, MPA, CSS, or RLV
3. Positive serology for ANCAd
  • a 1, 2, and 3 are required. CSS, Churg-Strauss syndrome; MPA, microscopic polyangiitis; RLV, renal limited vasculitis; WG, Wegener’s granulomatosis.

  • b Histologic confirmation: Findings of necrotizing vasculitis and pauci-immune necrotizing, crescentic glomerulonephritis.

  • c Renal involvement: Elevated serum creatinine (>1.3 mg/dl), or hematuria (>30 red blood cells per high-power field), or proteinuria (>1 g/24 h), or red cell casts.

  • d ANCA negativity is allowed if the disease is confirmed histologically.