Table 1.

Multivariate risk factors for ESRD and composite end point of ESRD or deatha

Coefficient (95% CI)HR (95% CI)χ2P
ESRD
    serum creatinine (mg/dl)1.28 (1.07 to 1.49)3.59 (2.90 to 4.45)137.7<0.0001
    log (UACR)1.96 (1.55 to 2.38)7.12 (4.70 to 10.80)85.5<0.0001
    serum albumin (mg/dl)−0.78 (−1.09 to −0.48)0.46 (0.34 to 0.62)25.1<0.0001
    hemoglobin (g/dl)−0.11 (−0.18 to −0.04)0.90 (0.84 to 0.96)10.60.0011
ESRD or death
    serum creatinine (mg/dl)0.97 (0.80 to 1.14)2.63 (2.22 to 3.11)123.6<0.0001
    log (UACR)1.14 (0.86 to 1.43)3.14 (2.35 to 4.19)60.5<0.0001
    serum albumin (mg/dl)−0.61 (−0.86 to −0.35)0.54 (0.42 to 0.70)22.0<0.0001
    HbA1c (%)0.08 (0.03 to 0.13)1.08 (1.03 to 1.14)8.50.0036
    hemoglobin (g/dl)−0.07 (−0.12 to −0.02)0.93 (0.89 to 0.98)6.80.0089
  • a CI, confidence interval; HbA1c, glycosylated hemoglobin; UACR, urinary albumin:creatinine ratio. To convert urinary UACR in mg/g to mg/mmol, multiply by 0.113; serum creatinine in mg/dl to μmol/L, multiply by 88.4; hemoglobin in g/dl to g/L, multiply by 10; and serum albumin in mg/dl to g/L, multiply by 10.\