Table 2.

BP and main clinical and laboratory parameters in responders (TI score < 1.7) and nonresponders (TI score ≥ 1.7) who were included in the retrospective analyses and in patients who had IMN and were included in the prospective study on the basis of a TI score of <1.7a

Months
0123
Retrospective
    TI > 1.7
        SBP (mmHg)158.7 ± 36.1150.8 ± 23.1147.3 ± 18.4148.3 ± 15.7
        DBP (mmHg)89.5 ± 12.791.2 ± 11.489.7 ± 11.388.0 ± 10.6
        body weight (kg)75.2 ± 7.673.8 ± 8.175.0 ± 8.975.0 ± 8.2
        serum creatinine (mg/dl)2.1 ± 1.02.0 ± 1.02.1 ± 0.92.1 ± 0.9
        creatinine clearance (ml/min per 1.73 m2)48.6 ± 17.446.9 ± 16.747.3 ± 16.644.8 ± 14.2
        urinary protein excretion (g/24 h)9.4 ± 4.08.2 ± 3.38.1 ± 2.57.9 ± 3.3
        albumin fractional clearance (×1000)4.0 ± 3.53.5 ± 3.54.0 ± 2.03.2 ± 1.7
        serum albumin (mg/dl)2.6 ± 0.52.7 ± 0.52.7 ± 0.43.0 ± 0.6
        serum cholesterol (mg/dl)290.0 ± 81.6321.0 ± 68.9292.3 ± 55.7322.7 ± 54.8
        serum triglycerides (mg/dl)226.0 ± 94.6274.4 ± 111.7283.2 ± 117.8339.5 ± 152.6b
    TI < 1.7
        SBP (mmHg)129.3 ± 8.6126.9 ± 10.4126.0 ± 7.7126.3 ± 8.0
        DBP (mmHg)83.4 ± 7.579.3 ± 9.682.4 ± 6.081.1 ± 6.4
        body weight (kg)76.6 ± 16.6175.0 ± 15.773.9 ± 15.0b74.1 ± 14.8b
        serum creatinine (mg/dl)1.3 ± 0.41.3 ± 0.31.3 ± 0.51.3 ± 0.4
        creatinine clearance (ml/min per 1.73 m2)60.1 ± 35.472.4 ± 26.369.8 ± 26.374.1 ± 20.8
        urinary protein excretion (g/24 h)9.1 ± 4.04.2 ± 2.7c4.5 ± 2.8c4.6 ± 3.5c
        albumin fractional clearance (×1000)2.7 ± 2.31.5 ± 1.5d0.9 ± 1.1d1.0 ± 1.2d
        serum albumin (mg/dl)2.6 ± 0.52.8 ± 0.33.0 ± 0.3b3.0 ± 0.2b
        serum cholesterol (mg/dl)237.5 ± 74.0242.8 ± 80.5223.4 ± 59.9215.3 ± 50.9
        serum triglycerides (mg/dl)163.3 ± 74.4167.0 ± 76.7156.4 ± 74.6177.4 ± 82.4
Prospective (TI < 1.7)
    SBP (mmHg)128.4 ± 11.2133.1 ± 21.5130.6 ± 14.9129.9 ± 13.3
    DBP (mmHg)77.9 ± 11.478.1 ± 11.875.8 ± 10.679.8 ± 11.1
    body weight (kg)78.1 ± 16.677.9 ± 16.377.8 ± 15.677.7 ± 15.2
    serum creatinine (mg/dl)1.0 ± 0.31.0 ± 0.21.0 ± 0.31.0 ± 0.2
    creatinine clearance (ml/min per 1.73 m2)95.6 ± 20.3102.6 ± 21.3105.9 ± 26.397.8 ± 19.8
    urinary protein excretion (g/24 h)8.9 ± 5.36.5 ± 3.5b5.4 ± 3.9d4.9 ± 3.9c
    albumin fractional clearance (×1000)2.2 ± 1.41.7 ± 0.81.2 ± 1.0b1.1 ± 1.0b
    serum albumin (mg/dl)2.2 ± 0.62.5 ± 0.4d2.6 ± 0.6d2.8 ± 0.5d
    serum cholesterol (mg/dl)270.1 ± 73.2270.9 ± 81.7246.4 ± 44.2219.8 ± 46.9
    serum triglycerides (mg/dl)122.0 ± 70.3140.9 ± 79.8146.9 ± 98.6145.1 ± 75.4
  • a DBP, diastolic BP; SBP, systolic BP.

  • b P < 0.05,

  • c P < 0.01,

  • d P < 0.01 versus month 0.\