Interagency Registry for Mechanically Assisted Circulatory Support scale for classifying patients with advanced heart failure
Profile | Description |
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INTERMACS 1 | Hemodynamic instability in spite of increasing doses of catecholamines and/or mechanical circulatory support with critical hypoperfusion of end organs (severe cardiogenic shock) |
INTERMACS 2 | Intravenous inotropic support with acceptable BP but rapid deterioration of kidney function, nutritional status, or signs of congestion |
INTERMACS 3 | Hemodynamic stability with low or intermediate (but necessary due to hypotension) doses of inotropic support, worsening of symptoms, or progressive kidney failure |
INTERMACS 4 | Temporary cessation of inotropic support is possible, but patient presents frequently with symptom recurrence and typically with fluid overload |
INTERMACS 5 | Complete cessation of physical activity; stable at rest but frequently with moderate water retention and some level of kidney dysfunction |
INTERMACS 6 | Minor limitation of physical activity and absence of congestion while at rest; easily fatigued by light activity |
INTERMACS 7 | Patient in NYHA functional class IIa or IIIb with no current or recent unstable water balance |
Adapted from INTERMACS. INTERMACS, Interagency Registry for Mechanically Assisted Circulatory Support; NYHA, New York Heart Association.
↵a NYHA class II: slight limitation of physical activity; comfortable at rest but ordinary physical activity results in fatigue, palpitation, or dyspnea.
↵b NYHA class III: marked limitation of physical activity; comfortable at rest but less than ordinary physical activity results in fatigue, palpitation, or dyspnea.