Table 1.

Clinical findings and outcomesa

Patient
12345678
Age (y)6753616063655457
Racewhitewhitewhitewhitewhitewhitewhiteblack
Gendermalefemalefemalemalefemalemalefemalefemale
PresentationARFARFARFARFARFARFARFARF
Hypertensionyesnonoyesyesyesnoyes
Creatinine (mg/dl)3.21.52.02.13.11.91.82.6
GFR by MDRD (32) (ml/min)35.838.036.049.520.847.048.022.5
24-h urine protein (g)0.2000.5000.225U1.5020.0760.3881.071
Presumed cause of AINciprofloxacinunknownMCTDpANCAdrug-inducedunknownunknownsarcoidosis
Renal biopsy findingsAIN with eosinophilsAINAINGINAIN with eosinophilsAINAINGIN
Treatment
    steroid courses22111111
    max MMF daily dose (mg)15001500200010001500200015002000
    MMF duration (mo)3223292425133414
Follow-up
    duration, after MMF (mo)88503800
    creatinine (mg/dl)1.70.81.72.01.12.01.52.1
  • a AIN, acute interstitial nephritis; ARF, acute renal failure; GIN, granulomatous interstitial nephritis; MCTD, mixed connective tissue disease; MDRD, Modification of Diet in Renal Disease; MMF, mycophenolate mofetil; pANCA, perinuclear anti-neutrophil cytoplasmic antibody.