Table 2.

Comparison of selected renal biopsy features in the three groups of patients

Histopathologic FeaturePrednisone GroupO3FA GroupPlacebo GroupP Difference
No. of patients293129
Time interval between renal biopsy and study entry (mo)14 ± 1916 ± 279 ± 130.60,a 0.45b
No. of glomeruli (%)20 ± 919 ± 2617 ± 90.72,a 0.77b
Endocapillary hypercellularity (%)26 ± 2237 ± 2944 ± 250.04,a 0.59b
Cellular or fibrocellular crescents (%)5 ± 66 ± 99 ± 90.17,a 0.45b
Fibrotic crescents (%)9 ± 910 ± 1213 ± 150.60,a 0.71b
Segmental glomerulosclerosis (%)23 ± 1427 ± 1930 ± 180.35,a 0.89b
Interstitial fibrosis (grades 1 to 4)1.4 ± 0.91.4 ± 0.81.2 ± 0.70.42,a 0.53b
  • a Prednisone group versus placebo group.

  • b O3FA group versus placebo group.