Table 3.

Cox model: Graft and recipient survivala

CharacteristicsGraft SurvivalRecipient Survival
HR (95% CI)PHR (95% CI)P
Recipient
    age (per year)1.01 (1.01 to 1.01)<0.0011.04 (1.03 to 1.04)<0.001
    female0.96 (0.90 to 1.02)0.1690.93 (0.84 to 1.03)0.140
    race
        whiteReferenceReferenceReferenceReference
        black1.25 (1.16 to 1.33)<0.00011.04 (0.94 to 1.15)0.429
        Asian0.72 (0.61 to 0.86)<0.0010.66 (0.51 to 0.84)<0.005
        other0.98 (0.85 to 1.13)0.7811.15 (0.94 to 1.39)0.175
    history of diabetes0.96 (0.82 to 1.13)0.6261.14 (0.94 to 1.39)0.197
    history of hypertension0.86 (0.78 to 0.95)<0.0050.71 (0.63 to 0.81)<0.001
    height (cm)1.00 ()0.99 to 1.00<0.011.00 (0.99 to 1.00)0.06
    weight (kg)1.00 (1.00 to 1.01)<0.0051.00 (1.00 to 1.00)0.63
    comorbidity score1.07 (1.00 to 1.15)<0.051.29 (1.19 to 1.40)<0.001
    total duration of pretransplantation ESRD    (per yr)1.00 (0.99 to 1.01)0.4741.04 (1.03 to 1.06)<0.001
    total no. of transplants1.40 (1.30 to 1.52)<0.0010.93 (0.81 to 1.07)0.322
    cause of ESRD
        diabetesReferenceReferenceReferenceReference
        hypertension0.99 (0.85 to 1.15)0.8480.96 (0.79 to 1.16)0.679
        glomerulonephritis0.89 (0.76 to 1.03)0.1220.79 (0.65 to 0.95)<0.05
        other0.91 (0.79 to 1.05)0.2070.88 (0.74 to 1.06)0.186
    most recent PRA level (%)1.00 (1.00 to 1.01)<0.051.00 (1.00 to 1.01)0.13
    peak PRA level (%)1.00 (1.00 to 1.00)0.7411.00 (1.00 to 1.00)0.267
    no. of HLA-matched antigens0.94 (0.92 to 0.96)<0.0010.93 (0.91 to 0.96)<0.001
Donor
    deceasedReferenceReferenceReferenceReference
    living0.72 (0.65 to 0.80)<0.0010.61 (0.53 to 0.71)<0.001
    age (per year)1.01 (1.01 to 1.01)<0.0011.01 (1.01 to 1.02)<0.001
    female1.03 (0.97 to 1.09)0.2981.00 (0.92 to 1.09)0.984
    race
        whiteReferenceReferenceReferenceReference
        black1.24 (1.14 to 1.34)<0.0011.25 (1.11 to 1.41)<0.001
        other1.20 (1.07 to 1.33)<0.0050.96 (0.81 to 1.15)0.676
    height (cm)1.00 (1.00 to 1.00)<0.0011.00 (1.00 to 1.00)<0.05
    weight (kg)1.00 (1.00 to 1.00)<0.0051.00 (0.99 to 1.00)<0.005
    cold ischemia time (hr)
        ≤6 hReferenceReferenceReferenceReference
        >6 and ≤140.83 (0.73 to 0.94)<0.0050.86 (0.72 to 1.04)0.117
        >14 and ≤190.93 (0.82 to 1.05)0.2480.98 (0.81 to 1.17)0.791
        >19 and ≤240.99 (0.88 to 1.12)0.9061.01 (0.84 to 1.21)0.920
        >24 and ≤300.94 (0.83 to 1.07)0.3540.98 (0.81 to 1.18)0.823
    no. of pretransplantation transfusions
        0ReferenceReferenceReferenceReference
        1 to 51.08 (1.02 to 1.15)<0.051.29 (1.18 to 1.41)<0.001
        6 to 101.07 (0.94 to 1.22)0.3281.31 (1.10 to 1.57)<0.005
        >101.28 (1.11 to 1.47)<0.0051.59 (1.31 to 1.94)<0.001
    % of ESRD time on HD1.00 (1.00 to 1.00)0.0691.00 (1.00 to 1.01)<0.05
    % of ESRD time on PD1.00 (1.00 to 1.00)<0.051.00 (1.00 to 1.00)0.283
    maintenance immunosuppressive regimen
        PCMReferenceReferenceReferenceReference
        PTM1.08 (1.01 to 1.15)<0.050.99 (0.90 to 1.10)0.901
        PCA1.14 (1.07 to 1.22)<0.0011.15 (1.04 to 1.26)<0.005
  • a CI, confidence interval; HR, hazard ratio.