Table 2.

Association of level of renal function with revascularization within 6 mo of diagnosis with critical limb ischemia

Level of Renal FunctionUnadjustedAdjusteda
All patients
    eGFR ≥601.00 (referent)1.00 (referent)
    eGFR 30 to 590.66 (0.59 to 0.74)0.84 (0.72 to 0.96)
    eGFR 15 to 290.34 (0.26 to 0.45)0.47 (0.35 to 0.65)
    eGFR <15 not on dialysis0.21 (0.12 to 0.39)0.32 (0.16 to 0.62)
    dialysis0.45 (0.35 to 0.57)0.62 (0.47 to 0.84)
Rest pain
    eGFR ≥601.00 (referent)1.00 (referent)
    eGFR 30 to 590.66 (0.52 to 0.83)0.86 (0.64 to 1.15)
    eGFR 15 to 290.21 (0.11 to 0.38)0.30 (0.15 to 0.62)
    eGFR <15 not on dialysis0.23 (0.02 to 2.56)0.32 (0.02 to 5.25)
    dialysis0.49 (0.25 to 0.99)0.65 (0.27 to 1.54)
Ischemic ulceration
    eGFR ≥601.00 (referent)1.00 (referent)
    eGFR 30 to 590.81 (0.66 to 0.98)0.89 (0.70 to 1.12)
    eGFR 15 to 290.35 (0.21 to 0.58)0.41 (0.23 to 0.74)
    eGFR <15 not on dialysis0.14 (0.03 to 0.61)0.20 (0.04 to 0.91)
    dialysis0.74 (0.50 to 1.09)0.79 (0.50 to 1.26)
Gangrene
    eGFR ≥601.00 (referent)1.00 (referent)
    eGFR 30 to 590.62 (0.50 to 0.77)0.79 (0.61 to 10.3)
    eGFR 15 to 290.60 (0.41 to 0.88)0.60 (0.38 to 0.95)
    eGFR <15 not on dialysis0.44 (0.22 to 0.91)0.32 (0.14 to 0.74)
    dialysis0.54 (0.38 to 0.77)0.47 (0.30 to 0.75)
  • a Adjusted for age; black race; diabetes; random serum glucose; history of coronary artery disease, congestive heart failure, hypertension, stroke, and chronic obstructive pulmonary disease (COPD); clinical presentation (rest pain, ischemic ulceration, or gangrene); distance from nearest veterans affairs (VA) medical center; census division of residence; Medicare coverage (non-Medicare, Medicare health maintenance organization [HMO], Medicare non-HMO); year of cohort entry; and VA medical center.