Table 4.

Outcome after renal transplantation in patients with non–Stx-HUS associated with mutation of MCP gene

Study (First Author, Year)PatientGenderFamilial HUSAge at HUS OnsetTime between HUS and DialysisaMCP MutationEffect of MutationHUS Recurrence after TROutcome after Transplantation
Present article6FNo25 yrNo recoveryC218TArg25StopNoFunctional graft at 9 yr
Richards, 200324MYes27 yrNo recovery6bp delLoss of 237Asp and 238SerNoFunctional graft at 16 yr
25MYes31 yrNo recovery6bp delLoss of 237Asp and 238SerNoFunctional graft at 23 yr
26MYes35 yrNo recovery6bp delLoss of 237Asp and 238SerNoFunctional graft at 13 yr, death
  • a Irreversible loss of renal function during the acute phase = no recovery.