Table 4.

Factors associated with eGFR 1 year post-transplant

Clinical CharacteristicsMean Change, ml/min per 1.73 m2 (SD)Unadjusted Difference, ml/min per 1.73 m2 (95% Confidence Interval)P ValueAdjusted Difference without Delayed Graft Function, ml/min per 1.73 m2 (95% Confidence Interval)aP ValueAdjusted Difference with Delayed Graft Function, ml/min per 1.73 m2 (95% Confidence Interval)aP Value
Pretransplant peritubular capillary density per 1% higher0.6 (0.1 to 1.0)0.011.3 (0.6 to 2.0)<0.0011.0 (0.1 to 1.9)0.03
Peritubular capillary change per 1% higher0.0 (−0.4 to 0.5)0.921.0 (0.3 to 1.8)0.0070.8 (−0.1 to 1.6)0.07
Postoperative graft function<0.001not included0.23
 Immediate graft function60.7 (15.6)00
 Delayed graft function51.1 (13.1)−9.2 (−13.7 to −4.6)−3.1 (−8.3 to 2.0)
Biopsy type<0.0010.0050.004
 For cause43.9 (15.7)000
 Surveillance59.0 (14.8)15.7 (8.6 to 22.8)10.5 (3.3 to 17.7)10.7 (3.5 to 17.0)
Donor sex0.0010.0050.004
 Man donor61.7 (15.7)000
 Woman donor54.1 (14.4)−7.5 (−11.8 to −3.3)−5.8 (−9.8 to −1.8)−5.9 (−9.9 to −1.9)
Donor BP0.010.190.17
 Normal BP58.9 (15.8)000
 Donor hypertension51.7 (11.4)−7.6 (−13.6 to −1.6)−3.7 (−9.3 to 1.9)−3.9 (−9.5 to 1.7)
Donor age per 10 yr higher−2.6 (−4.2 to −1.0)<0.001−1.0 (−2.6 to −0.7)0.24−1.0 (−2.7 to 0.1)0.21
Glomerulosclerosis on the pretransplant biopsy per 1% higher−0.7 (−1.1 to −0.3)0.001−0.6 (−1.1 to −0.1)0.01−0.6 (−1.1 to −0.1)0.02
ci score on the pretransplant biopsy per 1 point higher−3.0 (−7.0 to 1.0)0.141.9 (−2.6 to 6.4)0.412.1 (−2.4 to 6.6)0.36
No. of previous transplants0.130.440.51
 First transplants58.4 (15.7)000
 Repeated transplants53.3 (12.5)−5.1 (−11.7 to 1.5)−2.3 (−8.2 to 3.6)−2.0 (−7.9 to 3.9)
Cause of CKD0.030.030.03
 Other55.9 (15.4)000
 Glomerular diseases60.8 (15.0)4.9 (0.4 to 9.4)4.6 (0.5 to 8.7)4.7 (0.6 to 8.8)
  • ci, Banff score for interstitial fibrosis.

  • a All of the variables included in the multivariable model are listed in the table.