Table 3.

Transfusion and surgical/radiologic intervention complications stratified by region, year, and needle gauge

SubgroupPapers, nTransfusion or Intervention, nBiopsies, nEstimate95% Confidence IntervalI2, %Modifier Test: P Value
Transfusion
 America1531,029123,8640.0460[0.03 to 0.07]99.5
 Asia2319522,1410.0075[0.00 to 0.02]85.9
 Europe2118716,8000.0103[0.00 to 0.02]65.0<0.001
 Pre-200073312310.0172[0.00 to 0.04]69.0
 2000–20091711967590.0108[0.00 to 0.02]81.3
 2010–20183531,259154,8150.0187[0.01 to 0.03]99.80.49
 16 Gauge2121910,7110.0574[0.02 to 0.11]95.9
 18 Gauge93127770.1614[0.07 to 0.29]99.10.06
 Overall5931,411162,8050.0160[0.01 to 0.02]99.8
Surgical/radiologic intervention
 America19216124,6300.0047[0.00 to 0.01]80.3
 Asia234321,8970.0006[0.00 to 0.00]59.5
 Europe247417,4670.0052[0.00 to 0.01]62.80.04
 Pre-20009916450.0033[0.00 to 0.01]0.0
 2000–2009173466540.0029[0.00 to 0.01]35.2
 2010–201840290155,6950.0036[0.00 to 0.01]77.60.80
 16 Gauge245510,7990.0024[0.00 to 0.01]39.8
 18 Gauge111229940.0005[0.00 to 0.00]23.70.28
 Overall66333163,9940.0033[0.00 to 0.01]72.8