Table 4.

Incidence of AKI defined by different criteria and its association of in-hospital death in patients with coronavirus disease 2019

CriteriaIncidence, n (%)OR (95% CI)
KDIGO criteria99 (7)5.12 (2.70 to 9.72)
Criteria 1: increase in Scr by 50% within 14 d101 (7)4.89 (2.60 to 9.21)
Criteria 2: increase in Scr by 50% within hospital stay110 (8)5.39 (2.92 to 9.94)
Criteria 3: increase in Scr by 40% within 7 d140 (10)3.92 (2.27 to 6.76)
Criteria 4: increase in Scr by 30% within 7 d187 (13)2.33 (1.41 to 3.85)
Criteria 5: increase in Scr by 20% within 7 d286 (21)1.48 (0.94 to 2.32)
  • KDIGO criteria are an increase in Scr by 0.3 mg/dl within 48 hours or a 50% increase in SCr from the baseline within 7 days; in addition to an increase in Scr by 0.3 mg/dl within 48 hours, the expanded AKI criteria were defined as a relative slow increasing of, or a small increase in, serum creatinine. ORs were obtained in multivariable logistic regression models after adjustment for age, sex, disease severity, intensive care unit admission, lymphocyte count, and D-dimer level. OR, odds ratio; CI, confidence interval; KIDGO, Kidney Disease: Improving Global Outcomes; Scr, serum creatinine.