Table 3.

Preimplantation genetic testing and pregnancy outcomes

Patient Categoryn (%)Median per Couple of Cumulative Cycles (Interquartile Range)
Couples with at least one preimplantation genetic testing cyclea43 (44)
 Cycles with oocyte retrieval792 (1)
 Embryos for biopsy53710 (14)
  Of which embryos genetically unaffected and suitable for transferb190 (35)3 (5)
 Couples with one or more pregnancy going >12-wk gestational age31 (72)1 (1)
 Couples with one or more unaffected live births28
  Couples with one unaffected live birth24 (56)N/A
  Couples with more than unaffected live birth4 (9)N/A
 Duration from referral to first live birth, yrN/A2 (1)
Couples not proceeding with preimplantation genetic testing37 (38)
Pregnancies without preimplantation genetic testing going >12-wk gestational age19 (49)N/A
Terminations of pregnancy after diagnosis of affected fetus (either with fetal ultrasound or invasive prenatal diagnostics)3 (8)N/A
Live birthsc15 (41)N/A
  Of which known to be affected4 (27)N/A
  Of which not affected4 (27)
  Of which affected status unknownd7 (47)
Couples waiting for validation of the single-cell genetic test on June 1, 20199 (9)N/A
Couples not yet decided on June 1, 20199 (9)N/A
  • N/A, not applicable.

  • a Including couples not yet finished with the maximum of three reimbursed cycles on June 1, 2019.

  • b In 2%–3%, embryo quality after thawing was too poor to perform the genetic test; thus, they were not suitable for testing and transfer.

  • c One of 19 pregnancies going >12-wk gestational age resulted in a midtrimester loss.

  • d Not all have received genetic testing due to the patient being a minor.