Table 4.

Logistic regression analyses examining the association of nadir-to-peak serum creatinine (sCr) increments and discharge disposition among hospital survivors stratified by baseline eGFR

Subjects (%)Subjects Discharged to Facilities (%)Adjusted Odds Ratio (95% Confidence Interval)
Baseline eGFR of ≥60 ml/min per 1.73 m2
    total21,0616,279
    nadir-to-peak sCr increment (mg/dl)
        <0.217,117 (81.3)4,653 (27.2)1.0
        ≥0.23,944 (18.7)1,626 (41.2)1.57 (1.44 to 1.70)
Baseline eGFR of 30 to 59 ml/min per 1.73 m2
    total6,1542,843
    nadir-to-peak sCr increment (mg/dl)
        <0.34,879 (79.3)2,096 (42.9)1.0
        ≥0.31,275 (20.7)747 (58.6)1.80 (1.56 to 2.08)
Baseline eGFR of <30 ml/min per 1.73 m2
    total1,326705
    nadir-to-peak sCr increment (mg/dl)
        <0.5939 (70.8)473 (50.4)1.0
        ≥0.5387 (29.2)232 (59.9)1.71 (1.30 to 2.25)
  • The model is adjusted for age, gender, race, Deyo-Charlson comorbidity index, hospital service, sepsis, cardiac catheterization, coronary artery bypass grafting, abdominal surgery, and acute organ system dysfunction score. eGFR, estimated GFR.