Table 1.

Demographic, clinical, and biological characteristics at presentation

CharacteristicValue
Female/male, n (%)16/10 (61/39)
Age, years (mean ± SD) (range)52 ± 16 (29 to 77)
    ≥40 years, n (%)20 (77)
    <40 years, n (%)6 (23)
Ethnicity, n (%)
    Caucasian22 (85)
    other4 (15)
Proteinuria, g/24 h (mean ± SD) [range]5.3 ± 4.6 [1.4 to 10]
Serum albumin, g/L (mean ± SD) [range]26 ± 7 [13 to 46]
Total serum protein, g/L (mean ± SD) [range]55.1 ± 6.1 [46 to 65]
Nephrotic syndrome, n (%)22 (85)
Hematuria, n (%)21 of 24 (87.5)
Serum creatinine, μmol/L (mean ± SD) [range]211 ± 190 [45 to 814]
eGFR, ml/min per 1.73 m2 (mean ± SD) [range]49.3 ± 34.6 [10 to 130]
Renal dysfunction, n (%)14 (54)
Hypertension, n (%)16 of 24 (66.7)
Dysproteinemia, n (%)8 (30.7)
    serum paraprotein only6 (23)
    serum and urine paraprotein2 (7.7)
Hematological malignancy, n (%)9 of 26 (34.6)
Low C3, n (%)1 of 22 (4.5)
Low C4, n (%)3 of 22 (13.6)
Low C3 and C4, n (%)4 of 22 (18.1)
Adenopathy, n (%)2 (7.7)
Hepatosplenomegaly, n (%)1 (3.8)
  • eGFR, estimated GFR.