Table 2.

Cumulative incidence rates for mortality, kidney failure, and major adverse cardiovascular events in the total cohort and by serum uromodulin quartiles

EventTotal Cohort (0.0–490.4 ng/ml)Quartile 1 (≤55.6 ng/ml)Quartile 2 (>55.6–83.4 ng/ml)Quartile 3 (>83.4–125.3 ng/ml)Quartile 4 (>125.3 ng/ml)
All-cause mortality
 Events, n335145866341
 Incidence per person year, % (95% CI)1.1 (0.8 to 1.4)1.7 (1.2 to 2.3)0.9 (0.6 to 1.4)1.0 (0.7 to 1.4)0.6 (0.4 to 0.9)
Kidney failure
 Events, n22912264358
 Incidence per person year, % (95% CI)0.4 (0.3 to 0.6)0.9 (0.6 to 1.4)0.4 (0.3 to 0.7)0.2 (0.1 to 0.4)0.1 (0.0 to 0.1)
MACE
 Events, n4171521159159
 Incidence per person year, % (95% CI)4.8 (4.3 to 5.5)6.7 (5.8 to 7.8)5.5 (4.7 to 6.4)4.0 (0.3 to 4.8)3.2 (2.7 to 3.9)
  • MACE, major cardiovascular event—defined as a composite of fatal cardiovascular event, nonfatal myocardial infarction, nonfatal stroke, or incident peripheral vascular disease.