Table 3.

Association between systolic BP parameters and LVH (in cross-section) in unadjusted and adjusted analyses along with model discrimination

Systolic BP Metrics (n=533)Unadjusted OR (95% CI)aUnadjusted c-Statistic (95% CI)Adjusted OR (95% CI)a,bAdjusted c-Statistic (95% CI)b
Awake systolic BP load (every 10% higher)1.1 (1.0 to 1.3)0.61 (0.53 to 0.68)c1.1 (1.0 to 1.3)0.77 (0.72 to 0.83)c
Awake systolic BP index (every 0.1 higher)1.7 (1.2 to 2.3)0.62 (0.55 to 0.69)1.6 (1.1 to 2.3)0.78 (0.73 to 0.83)
Awake systolic BP load plus awake systolic BP index0.9 (0.7 to 1.2)
2.4 (1.0 to 5.6)
0.62 (0.55 to 0.69)0.8 (0.6 to 1.1)
2.7 (1.0 to 7.2)
0.78 (0.73 to 0.84)
Asleep systolic BP load (every 10% higher)1.1 (1.0 to 1.2)0.62 (0.55 to 0.69)c1.1 (1.0 to 1.2)0.77 (0.72 to 0.83)c
Asleep systolic BP index (every 0.1 higher)1.5 (1.1 to 2.0)0.63 (0.56 to 0.70)1.5 (1.1 to 2.0)0.78 (0.72 to 0.83)
Asleep systolic BP load plus asleep systolic BP index0.9 (0.8 to 1.2)
1.8 (0.9 to 3.6)
0.63 (0.56 to 0.71)0.9 (0.7 to 1.2)
1.8 (0.8 to 3.9)
0.78 (0.72 to 0.83)
  • LVH, left ventricular hypertrophy; OR, odds ratio.

  • a OR for every 0.1 higher systolic BP index or 10% higher systolic BP load.

  • b Adjusted for age, sex, race, cause of CKD, body mass index z-score, urine protein-creatinine ratio, antihypertensive use, and baseline eGFR (by bedside Schwartz), n=515 included due to missing covariates.

  • c Reference group for awake or asleep c-statistic comparisons.