Table 5.

Association of kidney solute clearances with symptoms (n=28)

Kidney/Peritoneal Solute ClearanceDSI Symptom ScoreKCCQ Overall Score
UnadjustedModel 1Model 2UnadjustedModel 1Model 2
β (95% CI)P Valueβ (95% CI)P Valueβ (95% CI)P Valueβ (95% CI)P Valueβ (95% CI)P Valueβ (95% CI)P Value
GFRurea+Cr−8 (−17 to 0.5)0.06−7 (−17 to 4)0.22NANA8 (−1 to 18)0.099 (−3 to 21)0.14NANA
Kidney secretion score (composite)−11 (−20 to −3)0.007a−11 (−20 to −1)0.03a−15 (−30 to 1)0.0611 (1 to 21)0.03a12 (0.5 to 23)0.04a13 (−5 to 31)0.16
Peritoneal secretion score (composite)1 (−8 to 11)0.761 (−9 to 11)0.80−1 (−11 to 10)0.90−9 (−20 to 1)0.07−9 (−20 to 2)0.12−7 (−19 to 5)0.23
  • Model 1 includes age and sex. Model 2 includes age, sex, and GFRurea+Cr. Values are expressed as the change in DSI or KCCQ summary scores per SD increase in GFRurea+Cr or composite solute clearance. DSI, Dialysis Symptom Index; KCCQ, Kansas City Cardiomyopathy Questionnaire; 95% CI, 95% confidence interval; NA, not applicable.

  • a Statistical significance at P value threshold of 0.05.