Table 7.

Summary of relative risk reduction in SHARP study

EndpointEvents (%)Relative Risk95% Confidence IntervalEndpoint Definition in the Trial
Studied treat.Control treat.
cardiovascular event (fatal and nonfatal)a701/4650 (15.1%)814/4620 (17.6%)0.87[0.79; 0.95]Major vascular event
All cause death1142/4650 (24.6%)1115/4620 (24.1%)1.02[0.95; 1.09]
End stage renal disease1057/4650 (22.7%)1084/4620 (23.5%)0.97[0.90; 1.04]
Coronary event213/4650 (4.6%)230/4620 (5.0%)0.92[0.77; 1.10]
Cancer438/4650 (9.4%)439/4620 (9.5%)0.99[0.87; 1.12]Any cancer incident