Table 4.

Quantification of the relationship between BP (independent variable) and LVMI (dependent variable) expressed in g/m2.7 via multiple linear regression

VariableModel A, Clinic SBP z-Scorer2 = 0.40, Adjusted r2 = 0.29
CoefficientSEMPVariance Inflation Factor
Clinic SBP z-scorea3.941.410.0081.41
BMI0.120.280.671.06
eGFR−0.090.100.371.58
Antihypertensive medication−0.652.220.771.13
Time-averaged log iPTH−0.281.590.861.38
Time-averaged serum Ca13.1715.260.391.44
Elemental Ca intake2.991.320.031.27
  • A separate model was constructed for each of the BP methods with adjustment for the same confounders throughout. Model A shows the results for the model using clinic SBP z-score; the coefficients for all confounders are also shown. Similar models (with confounders not shown) were constructed for clinic DBP z-score and clinic pulse pressure 24-hour and nocturnal BP readings (results in text and Supplementary Appendix Table 5). LVH was defined using age-specific reference intervals for normal children (19). “Time-averaged,” time-averaged value over preceding 18 months; serum Ca, serum-corrected Ca levels; elemental Ca intake, elemental Ca intake in g/d from prescribed Ca-containing phosphate binders.

  • a Coefficient interpretation is such that an increase in clinic SBP z-score of 1 unit is associated with an increase in LVMI of 3.94 g/m2.7.