Table 3.

Associations of quartiles of plasma carbamylated lipoproteins with primary and secondary kidney outcomes

QuartileDoubling of Serum CreatinineRapid Kidney Progression
No. of EventsHR (95% CI)P ValuePtrendNo. of EventsHR (95% CI)P ValuePtrend
Carbamylated LDL
 <274 µg/ml43Reference<0.00136Reference0.07
 ≥274 and <397 µg/ml571.25 (0.77 to 2.03)0.37420.86 (0.58 to 1.26)0.43
 ≥397 and <459 µg/ml781.96 (1.25 to 3.09)0.004511.29 (0.71 to 2.47)0.10
 ≥459 µg/ml922.21 (1.42 to 3.46)<0.001541.38 (0.93 to 2.05)0.11
Carbamylated HDL
 <29 µg/ml39Reference<0.00135Reference0.005
 ≥29 and <33 µg/ml431.04 (0.59 to 1.84)0.69400.97 (0.60 to 1.42)0.65
 ≥33 and <42 µg/ml701.65 (1.06 to 2.76)0.02471.13 (0.66 to 1.94)0.35
 ≥42 µg/ml1184.53 (2.87 to 7.13)<0.001611.98 (1.19 to 3.29)0.01
  • HR, hazard ratio; 95% CI, 95% confidence interval.